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From: Dave
Date: 02 Jun 2006
Time: 15:28:33 +1100
Remote Name: 59.167.75.50
Comments:
A quick search on Google:
"Vancomycin causes dangerous precipitation when infused with gelatin fluid"
We all seem to be quite blase when it comes to mixing different drugs.
Nurses on the other hand are quite rigid in their drug administration (The book says
we can't run morphine, ketamine and insulin so could we please have three IV's).
Nurses are also very conservative with their administration rates (genta over 1 hour,
vanco over 2 hours - no exceptions)
We, on the other hand, mix everything together.
I have personally seen:
Metronidazole bag (100mL), mixed with ampicillin and gentamicin ("the triple anti's
in one bag")
Remi and propofol ("ideal TIVA")
Propofol and phenylephrine ("Propofol Gold" - This improved IV induction agent
causes less hypotension than Propofol)
Midaz and fentanyl ("Fantazalam" - quite a legitimate mix I think as per product info)
Various mixtures of dexa, maxolon, ondansetron, droperidol ("Ideal antiemetic")
Personally I believe it is outright dangerous, and shows a lack of understanding of the
physiochemical properties of the drugs. With the naked eye we can only detect the
gross reactions, and with so many possible combinations, it's not possible to list all the
incompatibilites.
Would you think it would just be safer to not mix drugs except for the recognised
combinations (morph and midaz, local and adrenaline) etc